Biofilm are widely recognised as sources of a persistent wound infection that are tolerant to antibiotics, antiseptics and the host immune system.

Manual debridement is the cornerstone of biofilm removal

In addition, there is now published consensus that augmenting manual strategies with a solution such as those containing hypochlorous acid to enhance debridement outcomes in replacement of passive solutions such as saline or water may be vital for improving the management of wounds with a high bacterial load such as chronic wounds.