Discover the different applications of women’s health
Microcyn® Technology
- Dermatology
- Woman's Health
- Nasal
- Ophthalmology
- Oral
- Pediatric
- Wound
Microcyn Technology
Microcyn® Technology
Safe as Water
In-vitro and clinical studies of Hypochlorous Acid (HOCl) show it to have impressive antipruritic, antimicrobial and anti-inflammatory properties. The Microcyn® Technology not only optimizes HOCl for superior efficacy and safety, it guarantees potency for the life of the product. With virtually no side effects or contraindications, you can utilize Microcyn®-based products as often as needed to cleanse skin, relieve irritations and restore your well-being and peace of mind.
CLEANSE
RELIEVE
RESTORE
Triple Mode of Action 3X
Based on one of the body’s most important molecules, Hypochlorous acid (HOCl), Microcyn® Technology has a
Triple Mode of Action and profound impact on infection, inflammation and scarring:
ANTI-MICROBIAL
In-vitro and clinical studies of Microcyn Technology breaks down the biofilm along with having impressive anti-pruritic, anti-microbial, anti-viral and anti-inflammatory properties.
ANTI-INFLAMMATORY
A powerful anti-inflammatory, our products treat common conditions while reducing infections, itch, pain, scarring and harmful inflammatory responses.
REGENERATIVE
A gentle and safe solution that increases blood/oxygen flow to the wound, resulting in faster, more effective healing.
Microcyn® Technology Applications
CLEANSE
Safely eradicates biofilm and other irritants.
Time Kill Study: In Vitro in solution HOCl Eradication of Pathogens1
Greater than 99% reduction in killing 23 different microorganisms
Biofilm formation is recognized as a serious problem in chronic wound infections. HOCl has antibiofilm activity6 and actively breaks down biofilm and kills microorganisms within the biofilm. Biofilm characteristics include:
Complex structure of microorganisms that generate a protective shell, allowing bacteria to collect and proliferate
Most microorganisms that form biofilms found growing in microbial infection Adheres to chronic wounds, makes phagocytosis difficult, and increases resistance to antibiotics
RELIEVE
Reduces inflammation, pain, itch and swelling fast.
Study 1: Open-Label Study2
Open-label, single-arm study over 7 days
Results
HOCl rapidly reduces pruritus in mild-to-moderate atopic dermatitis (AD)
Study 2: Randomized, Blinded, Controlled Study3
- 72-hour study
- Treated group (n=19): HOCl BID
Untreated group (n=10): No treatment
Results
The mean pruritus VAS scores saw a greater improvement among the treated group than the untreated group between baseline and 72 hours post application
Microcyn Technology for Inhibition of Mast Cell Degranulation
- Prevents allergen and calcium-induced mast cell degranulation for up to 8 hours after a single exposure in vitro
- Reduces wound inflammation that inhibits healing
- Stabilizes the mast cell membrane to inhibit the cell machinery for granule secretion, while not altering the signal transduction pathways or calcium mobilization
- Inhibits degranulation stimulated by antigen or calcium ionophore
RESTORE
Increasing oxygen to the area in need helps accelerate the body’s natural healing process.
Increases Oxygenation5
Provides higher levels of oxygen at a wound site after application Elevated blood and oxygen flow increases wound-healing nutrients HOCl is a known vasodilator
Assists Wound Healing6
Wound healing involves a complex sequence of events. Fibroblasts are the primary synthetic cells in the repair process of most structural proteins used during tissue reconstruction.
At lower concentrations of HOCl, the percentage of fibroblast migration exceeded that of the control at 24 hours.
Microcyn® Technology is suitable for
the following indications
Based on one of the body’s most important molecules, Hypochlorous acid (HOCl), Microcyn® Technology has a
Triple Mode of Action and profound impact on infection, inflammation and scarring:
Wound Care
Skin Care
Nasal and Eye Care
Oral and Dental Care
Disinfectants & Sanitizers
Animal Care
Unique Chemistry
The main component, hypochlorous acid (HOCl), is naturally produced as part of our immune system during phagocytosis. When neutrophils encounter bacteria or other pathogens, the neutrophils engulf it, generate HOCl and instantly destroys the microorganism. This process is called the “oxidative burst”.
During the activation of neutrophils, ‘respiratory bursts’ generate hydrogen peroxide (H2O2) and the activated granule enzyme myeloperoxidase converts H2O2 into hypochlorous acid (HOCl).
Unique Chemistry
The main component, hypochlorous acid (HOCl), is naturally produced as part of our immune system during phagocytosis. When neutrophils encounter bacteria or other pathogens, the neutrophils engulf it, generate HOCl and instantly destroys the microorganism. This process is called the “oxidative burst”.
During the activation of neutrophils, ‘respiratory bursts’ generate hydrogen peroxide (H2O2) and the activated granule enzyme myeloperoxidase converts H2O2 into hypochlorous acid (HOCl).
Refrences:
1. Data on File. IntradermPharmaceuticals. 2. Draelos Z, Cash K. Evaluation of a gel formulation of hypochlorous acid and sodium hypochlorite to reduce pruritus in mild to moderate atopic dermatitis. Poster presented at: The Winter Clinical Dermatology Conference. January 14-19, 2012; Maui, HI. 3. Berman B, Nestor M. Investigator blinded randomized study evaluation HOCl in the treatment of atopic dermatitis-associated pruritus. Poster presented at: The Fall Clinical Dermatology Conference. Oct 12-15, 2017; Las Vegas, NV. 4. Medina-Tamayo J, Sánchez-Miranda E, Ballez-Tapia H, et al. Super-oxidized solution inhibits IgE-antigen-induced degranulation and cytokine release in mast cells. Int Immunopharmacol. 2007; 7(8): 1013-2014. 5. Bongiovanni CM. Superoxidized water improves wound care outcomes in diabetic patients. Available at: http://www.microdacyn.pl/pdf/7ART-02-Bongiovanni-DMC-05-2006.pdf. Accessed September 9, 2017. 6. Sakayra S, gunay N, Karakulak M, et al. Hypochlorous acid: An ideal wound care agent with powerful microbicidal, antibiofilm, and wound healing potency. Wounds. 2014;26(12):342-350.
Give us an opportunity
to get back to you with a solution.
[contact-form-7 id="610" title="Contact form 1"]